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Introductory seminar on nonlinear dynamics of DNA
2017-05-05  【 】【打印】【关闭

Institute of Theoretical Physics

Chinese Academy of Sciences

 Key Laboratory of Theoretical Physics

Seminar

Title

题目

Introductory seminar on nonlinear dynamics of DNA

Speaker

报告人

Dr. M. Vanitha

Affiliation

所在单位

ITP-CAS

Date

日期

05 May 2017, Friday: 15:45--16:45

Venue

地点

Conference Hall 322, ITP
 

Abstract

摘要

In this introductory seminar talk, I will summarise my previous research accomplishments on base pair opening in DNA double helical molecule in the form of solitons. Base pair opening in an inhomogenous double helical molecular chain with flexible strands is studied by solving the governing dynamical equations analytically and numerically. The results show that inhomogeneity in stacking and hydrogen bonds in localized and periodic forms and the helicity do not alter the amplitude of the bubble soliton. However the flexibility of the strands makes the amplitude to damp. On the otherhand the velocity of the bubble soliton is unaltered. Further the above effects introduce small fluctuation in the tail of the bubble soliton without affecting the robust nature of the soliton during propagation. Based on this well-established nonlinear dynamical framework to account for DNA denaturation--annealing dynamics, I will briefly discuss our initial effort to understand the dynamics of coordinated neural activity in the observed neural dynamics from place cell recordings from mice, including mouse models that are relevant to autism and mental illness in general. I will conclude my talk with the current topic of my interest on networks.

Contact person

所内联系人

Hai-Jun Zhou
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