- Title题目 (Seminar)Designing the Morphology of Separated Phases in Multicomponent Liquid Mixtures
- Speaker报告人
- Date日期
- Venue地点
CAS Key Laboratory of Theoretical Physics | |
Institute of Theoretical Physics | |
Chinese Academy of Sciences | |
Lunch Seminar | |
Title 题目 |
Designing the Morphology of Separated Phases in Multicomponent Liquid Mixtures |
Speaker 报告人 |
毛晟 (助理教授、特聘研究员) |
Affiliation 所在单位 |
北京大学工学院力学与工程科学系 |
Date 日期 |
2021年4月15日(周四)14:00 |
Venue 地点 |
6620 |
Contact Person 所内联系人 |
孟凡龙 |
Abstract 摘要 |
Phase separation of multicomponent liquid mixtures plays an integral part in many processes ranging from industry to cell biology. While the physics of binary and ternary liquid mixtures is well-understood, the thermodynamic properties of N-component mixtures with N>3 remains relatively unexplored. This makes it challenging to understand how cells control concentrations of molecules and their interactions to navigate phase diagrams to achieve target structures. To address this issue, we developed novel algorithms for constructing phase diagrams and for predicting the morphology of separated phases. To determine the number of coexisting phases and their compositions, we developed a new algorithm for constructing complete phase diagrams, based on numerical convexification of the discretized free energy landscape. Furthermore, we developed a graph theory approach to predict the topology of coexisting phases from a given set of surface energies (forward problem), enumerate all topologically distinct morphologies, and reverse engineer conditions for surface energies that produce the target morphology (inverse problem). |